this post was submitted on 07 May 2025
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[–] peoplebeproblems@midwest.social 72 points 7 months ago (8 children)

Wegovy/Saxenda whatever others are (GLP-1) inhibitors aren't a scam, they work.

They are absurdly expensive for the benefit they bring. Of course, fat lot of good it does if you don't use it to the full extent so you can actually get off of it.

[–] Trimatrix@lemmy.world 18 points 7 months ago (2 children)

Or get caught up in the crossfire where Metformin makes you shit your pants and a new drug for managing your A1C comes out (ozempic) which doesn’t make you shit your pants. Only for a few years later get denied insurance coverage for it because you obviously are using it to lose weight.

[–] grysbok@lemmy.sdf.org 7 points 7 months ago (1 children)

In theory once you stay at a dosage of metformin for long enough the unfortunate side effects go away. In practice it's been a year and I still can't trust a fart.

[–] RustyShackleford@literature.cafe 6 points 7 months ago

You guys trust your farts? I always presume each oncoming fart is a world ending disaster.

[–] Guidy@lemmy.world 2 points 7 months ago (1 children)

I got denied coverage because I don’t have type 2 diabetes. My main doctor confirmed I’m pre-pre-diabetic.

Or I was.

I pay for the medication myself and the diet they have me on is literally called the Insulin Resistance Diet.

Not only have I lost just over 30 pounds in 90 days but I’m also clearly healthier just because of this diet. (At my height and weight 30 pounds isn’t shit, but I’m only just getting started.)

[–] SolarMonkey@slrpnk.net 1 points 7 months ago

Proud of you random internet stranger! Keep up the good work! It’s going to be super duper worth it!

[–] lupusblackfur@lemmy.world 9 points 7 months ago

fat lot of good

Pun intended...??

😂

[–] nibbler@discuss.tchncs.de 7 points 7 months ago

The pricing is absurd. In Denmark it's like $80 for four weeks. in USA it starts at $1000. But medicine in USA is a whole other can of worms.

In Germany it starts at $300 (2.5mg/week) and goes up to $540 (15mg/week). But then if you get a 15mg/week prescription and happen to only need 5mg/week (possibly supported by taking it more often than once a week), and also make use of the 1.3 (my guesstimate) extra doses that are in the syringe (but a bit difficult to extract) you pay like $120/month. This is what a proper gym costs in my area. And honestly, you safe on food, too. And on your weight watchers subscription!

[–] CmdrShepard42@lemm.ee 4 points 7 months ago* (last edited 7 months ago) (3 children)

I dunno anything about these drugs but I remember the diet drug fad in the '90s and the disastrous consequences and side effects that came from it. I'm sure these aren't going to give heart attacks to a bunch of people, but I have a hard time believing there isn't some sort of cost to pay for a magic pill that makes you skinny. I'm willing to admit that my view is tainted by the past and will once again state that I know nothing about these pills specifically so I could be completely off base here.

[–] Ledericas@lemm.ee 4 points 7 months ago (1 children)

could you be referring to this drug, Fenfluramine/phentermine.

[–] TheRealKuni@midwest.social 3 points 7 months ago

Good ol’ fen-phen.

[–] lennybird@lemmy.world 4 points 7 months ago (1 children)

I'll just say that my wife works in medicine and you have to stop Oz3mpic 24 hours before surgery because of the added risk of aspiration due to the stomach retaining food contents for longer. Seems to possibly put strain on the pancreas (pancreatitis a side effect).

That doesn't sit well with me. Neither does it fix the core problem of what caused the vast majority of weight gain cases: poor dietary habits. Then again, our society has short-circuited evolutionary dopamine-driven behavior so it may necessitate intervention to re-wire it back.

[–] nibbler@discuss.tchncs.de 4 points 7 months ago (1 children)

Ozempic is typically taken once a week. The half-life of Ozempic is about a week. Stopping Ozempic "24 hours before surgery" does not make any sense.

[–] lennybird@lemmy.world 4 points 7 months ago* (last edited 7 months ago)

I might have that wrong and it may be a full week. I'll ask them when I get a chance and update.

Edit: Yeah my mistake; it's a week.

[–] Merva@sh.itjust.works 1 points 7 months ago

but I have a hard time believing there isn’t some sort of cost to pay for a magic pill that makes you skinny

There is a cost. It is called money, it is incredibly expensive, and they need to take it for life.

[–] matdave@lemmy.ml 4 points 7 months ago

They also banned the knock off versions a little while ago since the name brands were no longer in shortage. WW had HEAVILY pivoted into trying to sell subscriptions to those and lost big.

[–] Kecessa@sh.itjust.works 4 points 7 months ago (2 children)

They work!*

*aslongasyoudontstop

[–] nibbler@discuss.tchncs.de 4 points 7 months ago (1 children)

Same as for working out, controlling your calorie intake etc.

[–] Kecessa@sh.itjust.works 1 points 7 months ago

Bingo, those medications are as effective as any other diet or change of habits, if you have a problematic relationship with food you need to fix the reason behind it otherwise the moment you stop you'll gain your weight back.

[–] Monstrosity@lemm.ee 1 points 7 months ago

There are other, cheaper options as well but they require consistent diet/exercise on top of the Rx, so I think they are less popular for that.