I don't really agree with that. A program could break out of the sandbox and get to know the things around it. In fact, there are many programs that interact with the real world, gathering information about it and acting on it.

If there was something like an actually sentient program, it would be totally conceivable that said program could use cameras, microphones and other sensors to get to know its programmer.

The difference between the science and things considered supernatural is that one is something we have a solid understanding of and the other is speculation.

If there's an unexplained phenomenon and we find a solid explanation for it, it becomes science. Weather and other natural phenomena used to be in the realm of the supernatural, same as dragon bones, mermaid bones and the kraken. Until we found out what they really were and how they worked.

If magic were to exist in reality, it wouldn't be magic but instead just a branch of science.

A lot of things we can do nowadays would be called magic a few centuries ago. I mean, we can literally make frogs float in thin air. We can make incredible amounts of power from some magic rocks (nuclear power). We can even inscribe magic patterns into sand to make it think and talk (computers).

So coming back to the beginning: If we talk about something like a Simulation Hypothesis scenario (which is de facto identical to a scenario where God exists outside of our plane of existence, however that is defined), it's totally in the realm of possibility of that scenario that the simulated could break out of the simulation.

Or in case of the Big Bang Theory, it would be theoretically possible to peek before the big bang.

I'm not saying that it is actually possible, but I'm saying that we can't summarily dismiss the possibility.