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dart board;; science bs
rule #1: be kind
sharper images of our body’s tiniest proteins
Ah! Don't look at my tiny proteins! 🫢 😳
Too late, everyone has seen your proteins now and they’re tiny
Hey! That's really personal!
This phase change boosts contrast for small molecules, such as hemoglobin, and for molecules and structures inside cells, such as the nucleus and mitochondria.
“With cryo-ET, we’re looking at small, very complicated cellular material that’s incredibly crowded inside the cell,” said Bridget Carragher, founding technical director of imaging at Biohub in Redwood City, California “It’s like a forest of trees, and you’re trying to find one leaf on one tree in there. Cryo-ET needs a dramatic step forward in contrast, so we can start to see what’s going on inside the cell. That’s what the laser phase plate promises to give us.”
So cool.