this post was submitted on 16 Jul 2026
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A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.

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[–] THE_GR8_MIKE@lemmy.world 14 points 1 week ago (4 children)

What about a high fat high carb diet?

Obesity is linked to higher risk for many cancers

[–] hakunawazo@lemmy.world 5 points 1 week ago* (last edited 1 week ago)

...asking for a very unhealthy friend...uhm...

[–] psud@aussie.zone 4 points 1 week ago

That'll make you fat and bring on metabolic syndrome and all that

[–] P00ptart@lemmy.world 4 points 1 week ago* (last edited 1 week ago) (1 children)

As long as it's high in saturated fats and simple carbs, you'll be fine. But don't do anything physically demanding, or could be considered exercise.

[–] medem@lemmy.wtf 3 points 1 week ago (2 children)

Didn't you mean complex carbs?

[–] P00ptart@lemmy.world 3 points 1 week ago (1 children)

Complex carbs are like corn and potatoes. They break down slower and give you more energy over time. They're not super great but simple carbs are like white bread and candy, which spike energy and blood sugar levels.

[–] Jake_Farm@sopuli.xyz 3 points 1 week ago (1 children)

So unsaturated fat and complex carbs

[–] P00ptart@lemmy.world 4 points 1 week ago* (last edited 1 week ago) (1 children)

Yes, if I wasn't joking. Hence the not doing anything physical.

Edit; whoops. I see my mistake. Fixed the unsaturated to saturated, thanks.

Edit: edit: stop ruining my poorly written jokes!

[–] Jake_Farm@sopuli.xyz 1 points 1 week ago (1 children)

You seem to have gone on an emotional rollercoaster

[–] P00ptart@lemmy.world 2 points 1 week ago

Not emotional, but cognitive. Lol

Been working overtime in a foundry during a heat wave. Brain no worky right.

[–] xep@discuss.online 2 points 1 week ago

But don’t do anything physically demanding, or could be considered exercise.

He's joking.

[–] dbtng@sh.itjust.works 10 points 1 week ago (4 children)

Judging from the comments, people are committed to their atkins thing.
I don't expect this to be well received.

Fiber. You need it. This 'ketogenic' thing is suicide.

[–] IronBird@lemmy.world 13 points 1 week ago (1 children)

you can eat plenty of fiber and still be keto

[–] psud@aussie.zone 1 points 1 week ago

Also you can eat none and be perfectly healthy

[–] HubertManne@piefed.social 5 points 1 week ago (1 children)

yeah after water and calories its sorta a toss up between fiber and vitamin C but you only need a bit of vitamin C. you need lots of fiber just like water and calories.

[–] psud@aussie.zone 2 points 1 week ago (2 children)

Laughs in no fibre for years

[–] HubertManne@piefed.social 6 points 1 week ago

that tracks.

[–] Atelopus-zeteki@fedia.io 2 points 1 week ago (1 children)

Mod for Keto and Carni communities, who acts kinda trolly sometimes, it seems. And yes, I'm outing you. I prefer that to blocking, as it lets me keep an eye on your posts/ comments. Have a nice day.

[–] psud@aussie.zone 3 points 1 week ago* (last edited 1 week ago)

Outing me for my diet? Right after I say what my diet is?

[–] Reddfugee42@lemmy.world 5 points 1 week ago (1 children)

Atkins explicitly allows fiber and explicitly states fiber carbs don't count when watching carbs. You should know about things you critique before you critique them.

[–] dbtng@sh.itjust.works 1 points 1 week ago* (last edited 1 week ago) (2 children)

'Atkins' has been thoroughly debunked. People should know better by now.
I was there for the start of that fad, and unfortunately for me, bought the bullshit.

[–] Reddfugee42@lemmy.world 2 points 1 week ago (1 children)

If by debunked, you mean repeatedly proven to be the fastest weight loss diet 😅

[–] dbtng@sh.itjust.works 0 points 2 days ago

Hey, poison yourself, that's fine. It's not so fine to push it on others.
By debunked, I mean its an extremely unhealthy way to live, and its gonna fuk your guts up. Enjoy your trip to the butt doctor.

[–] Zarobi@aussie.zone 1 points 1 week ago

Just a personal anecdote, but an Atkins brand meal replacement shake I used to consume had many times the listed B2 levels, because my pee turned radioactive yellow. It said 25%RDI, but ain't no way, it was more like 250% or more. I've never had that happen before, even when taking B2 supplements. It made me cautious what else is incorrect on the nutrition label and distrust the brand. Plus it's probably not great for your kidneys long term.

[–] psud@aussie.zone 1 points 1 week ago (1 children)

Can you point to research that says we require fibre?

[–] dbtng@sh.itjust.works 10 points 1 week ago (12 children)

I guess you are kidding, but sure. It's good to get the info out there. All ya gotta do is google it tho ...

Would you prefer Stanford, Harvard, Mayo Clinic, or NIH?

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It’s almost as if the most healthy diet is a diverse one.

[–] Jake_Farm@sopuli.xyz 3 points 1 week ago (1 children)

What about high protein moderate fat?

[–] psud@aussie.zone 3 points 1 week ago

You won't have enough energy. We need either fat or carbohydrates for energy

[–] psud@aussie.zone 1 points 1 week ago* (last edited 1 week ago) (1 children)

What were the mice fed? Is this like a vegetarian low carb diet where the fats come from factory fats - seed oils?

Does "susceptible mice" mean mice that are highly prone to cancer?

Were they also fed carcinogens?

There is reason to think that high meat, high animal fat diets are protective against cancer, as cancer depends on sugar

[–] jet@hackertalks.com 5 points 1 week ago (2 children)

What were the mice fed? Is this like a vegetarian low carb diet where the fats come from factory fats - seed oils?

this was the diet used https://researchdiets.com/en/formulas/d06040601 sucrose, corn starch, soybean oil, food dyes... you know... keto stuff.... 6% daily energy from soybean oil

Were they also fed carcinogens?

the mice were genetically engineered to develop tumors, so not fed, designed.

There is reason to think that high meat, high animal fat diets are protective against cancer, as cancer depends on sugar

This study isn't about keto, its about the pathway of tumor growth in genetically engineered tumor laden mice in a high fat diet.... unless your a mouse engineered to develop tumors genetically this doesn't apply to you.

[–] psud@aussie.zone 3 points 1 week ago (1 children)

So these mice were on a high carb diet with exogenous ketones? 6% energy from fat isn't ketogenic

[–] jet@hackertalks.com 3 points 1 week ago (1 children)

6% from soybean oil, total energy from fat was about 80%, except they didn't count fibre in the diet as carbohydrates... if you do that its a 15% carb diet.

[–] psud@aussie.zone 3 points 1 week ago* (last edited 1 week ago)

I don't tolerate sugar or fibre well, and I'll avoid plant oils in general

[–] psud@aussie.zone 3 points 1 week ago (1 children)

Ok so I'm not a mouse, I'm not from a line deliberately bred for cancer, and my diet has none of those things; my 80% energy from fat is from beef fat. I think I'm not going to worry about this

[–] jet@hackertalks.com 3 points 1 week ago (1 children)

also 50g of fibre in the feed diet, maybe the tumors are responding to fibre?

i'm just skimming right now, but the papers studies each used 2-4 mice, and are not powered at all. it's hard to say even if you WERE a PPAR-CPT1A engineered mouse that these results are relevant... they knocked out ketogenesis in a few of the mice and still saw tumor growth.... let's not forget the genetic engineering here not only induces tumors, but also suppresses bhb production... so maybe these tumors respond well to fatty acids, but would be suppressed by healthy bhb production and ketone metabolism... this paper doesn't know. it's possible the net effect of a healthy ketogenic metabolism would be enough in non-genetically engineered mice to reduce the tumors.... they didn't test that.

plus...... they didn't measure all cause mortality! so we just know tumor growth for a window... why not actually get all cause mortality data? nothing ruins short term results like long term data.

the fact we have human interventional studies directly linking tumor growth to glucose intake, and in this mice study we see the opposite only in their genetically engineered tumors.... i'm not sure we can make any meaningful conclusions from that.

[–] psud@aussie.zone 3 points 1 week ago (1 children)

They conclude the cancers are triggered by the fats not ketones based on the study title (I haven't had time to read the study yet)

[–] jet@hackertalks.com 4 points 1 week ago* (last edited 1 week ago)

the study isn't open access, I'm pretty sure nobody has read the study including the nature "article" author.

it's pretty bad form, and intellectually dishonest, to share a paywalled article on a paywalled paper, just because you like the title... ensuring nobody will read what is actually said is pretty anti-science.

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