Sunless Sea, Sunless Skies and Stardew Valley have native Linux Support. For Stardew, even the third modding API works flawlessly for me.
For the other ones, they are reported to run well on protondb.com, which is a good place to check Linux support (not only for Steam games). The reports there usually also list, which proton version works well.
If it is anything like other surgeries done at vets, the risky part with such an old animal is the sedation, not the surgery itself. And with animals you usually need to fully sedate them, as they don't understand that they need to stay still.