100K Penguins! Bazzite hits 100,000 weekly active devices, growing 14k devices in the past 3 months.
(universal-blue.discourse.group)
Homebrew is the first go-to for software. Distrobox for more heavy-duty things.
There's also ujust which has a handful of things made specifically for Bazzite. And AppImages work just like on any other distro.
The only thing that's really discouraged is rpm-ostree. That's a last resort, and almost never necessary.