Microblog Memes

Only up to 100 mg? Such a tiny amount of substance could never have an impact on a human body! That’s why when I take a 50 mg edible absolutely nothing happens.

You are delusional, and completely misinterpreting that study and Wikipedia. Like, reading your other comment you did a “lot of work” on - I’m kind of amazed - it reminds me of the kind of stuff that I’d see to back up Ivermectin being a miracle cure.

Nicotine induces epithelial–mesenchymal transition (EMT), which is one of the vital steps for the acquisition of malignant phenotype. This transition allows the cell to acquire migratory properties, which may facilitate cancer metastases (42). Nicotine decreases the tumor suppressor Chk2, which is activated by DNA damage. The decrease in Chk2 in cells exposed to nicotine suggests that nicotine may be capable of overriding DNA damage checkpoint activation, disrupting genetic surveillance, and increasing the risk of oncogenesis (43).

Since you seem very concerned with dosage:

Systemic intake of nicotine from standardized vaping and smoking sessions after overnight abstinence from nicotine has been estimated from area under the nicotine plasma concentration-time curve (AUC).50 Average nicotine intake from e-cigarettes was 0.9 mg compared to 2.2 mg from a cigarette. Nicotine intake was higher, averaging 1.8 mg, from variable power e-cigarettes. It is difficult to extrapolate from nicotine in the liquid to systemic dose. For example, assuming 1 to 1.5 mg nicotine per cigarette, a 5% nicotine JUUL pod containing 0.7 ml liquid with 59 mg/ml nicotine, or 41 mg nicotine, would equate to 27 to 41 cigarette equivalents. However, using both emission data in laboratory testing and human exposure studies, one 5% JUUL pod seems to be equivalent in systemic nicotine delivery to smoking around 18 cigarettes per day.51

Secondhand smoke is also harmful:

Prevalence of secondhand nicotine vape increased from 11.7% to 15.6% during the study period in this population. Prevalence of wheeze, bronchitic symptoms and shortness of breath ranged from 12.3% to 14.9%, 19.4% to 26.0% and 16.5% to 18.1%, respectively, during the study period. Associations of secondhand nicotine vape exposure with bronchitic symptoms (OR 1.40, 95% CI 1.06 to 1.84) and shortness of breath (OR 1.53, 95% CI 1.06 to 2.21) were observed after controlling for vaping, active and passive exposure to tobacco or cannabis, and demographic characteristics (age, gender, race/ethnicity and parental education). Stronger associations were observed when analysis was restricted to participants who were neither smokers nor vapers. There were no associations with wheezing after adjustment for confounders.

You have an addiction and are doing something that is harmful to your body. There is not an evil conspiracy by the government and research scientists to convince you that nicotine is bad for you, nicotine is bad for you.