I think the 20th and 21st century are a lot and we sort of have to take it in first, culturally.
I've seen "sci-fi" besides some twists, I'm not sure what the genre currently has to offer that's not either fulfilled or actively being worked on. Or we have no idea how to even approach the issue from scientific basics.
Like, give me a good sci-fi "what if" and I'm in. I just don't expect to find one in a bookstore.