I'm not sure about about using an older kernel.
I've already mentioned having issues with Flatpak's redundancy*, but I also imagine sandboxing could potentially have other issues too. Specifically I use Godot 4.6+ with bindings for a compiled language. (I haven't used it thus far, but Godot can potentially have a pipeline from Blender)
So, maybe something like that might be viable with a different package distribution system. I haven't looked into it though.
* and this could be another nVidia thing with the size of the driver?