You don't understand House, or psychiatry. You know, the thing you need a medical doctorate to do? The thing all MDs have to study even outside of the specialty?

He would absolutely hate himself for missing that risk in your profile and then do some Vicodin to forget. He wouldn't be shattered or anything but it would absolutely be a piece of the puzzle he missed and he'd hate that.

Edit: hell, Dr Kutner kills himself for that matter and there's an episode about House treating it like a murder because he refuses to admit he missed the signs

I think if you want to torture him, let him treat someone, and don't let him know if he was right or not.

Just take new poisons, viruses or whatever every time your condition improves. Then you'll be in control of the edging (so to say), and therefore also the final denial/ruin.