I've done a few cross country moves where I would only try to time out a stop for all three reasons at a time: restroom, refuel, meal. I was doing pretty great with only one stop every 4-5 hours or so, 14 hours of driving per day.

As an EV owner (and a parent who now usually has kids in the car), I go at a much more leisurely pace and don't need to do that kind of road trip anymore. But I totally get why it's the default for a lot of people trying to get from one place to another