I think the only locked down items where I live are alcohol (and probably media that is age restricted for +12).

Side note:
What I observed in a franchise supermarket:
Shop A: Near a substance abuse help center
Shop B: Outskirts of my hometown (The area would peobably called suburban in the US. But there are some industrial, multi-family homes and mixed single houses. So not a classic house to house with garden area like stereotypical. Town is in Germany).

Both stock the "Bombay Saphire Gin".
Shop A: Locked and needs an employee to open the case
Shop B: Open to grab.

Quite insightful how the area influcences the item presentation and (unrestricted) access.