Its not a great meme but its kind of true, at least for me, I'm someone who likes being alone a lot of the time and I don't like to be bothered when I'm doing my own thing. They could have replaced "wife " with anyone who lives with you and it would have the same effect.

Gotta be honest. Been with my partner over 10 yrs. This meme didn't say anything about "wife ruining the day." It was simply a joke about when you have a moment the partner can sometimes sense that.

Like this meme has never happened to you? You were never just chilling and the wife/partner comes in with something to do?

I'd be more inclined to see this as boomer shit if it followed up with Kermit putting a gun in his mouth to escape his wife.