Gotta be honest. Been with my partner over 10 yrs. This meme didn't say anything about "wife ruining the day." It was simply a joke about when you have a moment the partner can sometimes sense that.
Like this meme has never happened to you? You were never just chilling and the wife/partner comes in with something to do?
I'd be more inclined to see this as boomer shit if it followed up with Kermit putting a gun in his mouth to escape his wife.