Well, if you did the exact same production process, yes, but as I posited, you could just 3d render the whole thing, or speed up production with basically 3d blocked out scenes and then basically do rotoscoping off of that, to add more flair or details where its worth it.
Its... not like cel shaded video games have not been a thing for a while, its not like 3d rendered animes have not been a thing for a while.