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No. That is why I shared my configs. With opcache and opcache.validate_timestamps = 0 you don't have this problem anymore.
Of course you also need to enable opcache itself as well.
Or you have really slow spinning disks or something. Also be sure to use php 8.4.
Again, it works until it requires reloading, i.e. the next update of any component or the next restart of the server.
I'm also running an inode cache on the client side, on top of the persistent opcache, but due to the sheer number of files that Nextcloud consists of it still generates a frankly ridiculous amount of calls when it needs to invalidate the cache. If you're running on local drives then that's likely much less of an issue, regardless of what kind of drive it is, but this is hosted on machines that do not have any local storage.
Uh I see.